Epigenetyczna kontrola procesów komórkowych
[ 1 ] Instytut Chemii Bioorganicznej Polskiej Akademii Nauk, Polska Akademia Nauk | [ P ] pracownik
2018
artykuł naukowy
polski
EN Epigenetic control of the cellular processesCells of a multicellular organism are genetically identical but differ in structureand function. This heterogeneity is created by several epigenetic mechanismsduring the development of the organism. The epigenetic changes- including DNAmethylation, histone post-translational modifications, chromatin remodeling andRNA interference have all been shown to control chromatin structure and regu-late a plethora of cellular and organismal processes. There is a strong evidencethat epigenetics play a crucial role in the development of diseases such as cancer,schizophrenia or metabolic disorders. The epigenetic regulation underlie memo-ry formation or adaptation to external stimuli. The extent to which environmentaleffects can provoke epigenetic responses represents an exciting area of futureresearch. Here we review the current knowledge about the epigenetic mecha-nisms and their relation to the human health and disease.
115 - 128
CC BY (uznanie autorstwa)
ostateczna wersja opublikowana
06.2018
w momencie opublikowania
10
10