Metabolomic profiling of serum and exosomes isolated from head and neck cancer patients after radiotherapy
[ 1 ] Instytut Chemii Bioorganicznej Polskiej Akademii Nauk, Polska Akademia Nauk | [ P ] pracownik
2020
artykuł naukowy
angielski
EN Cancer radiotherapy (RT) induces the response of the whole body that could be detected at the blood level. Searching for new molecular signatures which could correlate with treatment response in cancer patients is of particular importance. Radiation-induced changes in proteome and transcriptome of serum have been widely described. However, metabolomic changes in serum, exosomes and other classes of small extracellular vesicles (EV) of cancer patients after RT have not been given as much attention. Metabolomics of serum and EV of cancer patients could provide a valuable insight into the response of both tumour and whole organism to the treatment. The aim of the study was to compare serum and EV metabolomic profiles in head and neck cancer (HNC) patients before and after RT.
1784511
ISEV2020 ELECTRONIC NETWORK, 20-22.07.2020, online, United States
CC BY-ND (uznanie autorstwa - bez utworów zależnych)
ostateczna wersja opublikowana
07.2020
w momencie opublikowania
200
200